Dr Michelle Henderson | Leukaemia Foundation

2019 recipient: Dr Michelle Henderson

Researcher Dr Michelle Henderson

Dr Michelle Henderson, Children’s Cancer Institute, Sydney.
Project title: Targeting the NAD pathway as a new therapeutic strategy for high-risk leukaemia in children.

Rapidly dividing cancer cells can be dependent on a cellular biochemical called nicotinamide adenine dinucleotide (NAD) as an energy source. The Henderson laboratory discovered a new drug that blocks the production of NAD and has remarkably strong anti-leukaemia activity, even against the most aggressive subtypes of leukaemia.

This proposal aims to develop this drug as a novel therapeutic strategy for aggressive leukaemia in children, to ultimately improve their survival and minimise the side effects of treatment.

Posted on February 5th, 2020

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