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Developing a new targeted therapy with minimal side effects and toxicity to improve the outcome of childhood AML

Jenny Wang
Dr Jenny Wang, Children’s Cancer Institute, Sydney.
Funding period: 2019-2022.

This research project is kindly supported through the Estate of Florence Brown.

Acute myeloid leukaemia (AML) is a fatal form of blood cancer in children. The survival of AML patients remains poor due to the return of disease after chemotherapy (relapse). Leukaemia stem cells (LSCs) are the major cause of relapse and Dr Wang and the team at the Children’s Cancer Institute are studying how to eradicate them without harming healthy cells.

This project will develop a novel LSC-targeted therapy with minimal side effects and toxicity that will improve the dismal outcome of childhood AML.