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Breakthrough chronic lymphocytic leukaemia (CLL) treatment now available for Australians

Monday, 25 February 2019

The Leukaemia Foundation welcomes the Federal Government’s announcement that the targeted cancer treatment Venetoclax (Venclexta®), will be added to Pharmaceutical Benefits Scheme (PBS) from 1 March 2019.

Venetoclax will be available in combination with rituximab for patients aged 18 years or older with relapsed or refractory chronic lymphocytic leukaemia (CLL), who have received at least one prior CLL therapy and who are unsuitable for treatment or retreatment with a purine analogue.

CLL is the most common form of leukaemia with close to 1,500 Australians expected to be diagnosed this year. It is a slow growing leukaemia that affects white blood cells. Symptoms may include swollen lymph nodes (glands) in the neck, groin and arms, tiredness, unexplained bruising and unintentional weight loss.

A Leukaemia Foundation spokesperson said, “This is great news for Australians diagnosed with CLL. Having affordable access to breakthrough treatments is vital for improving quality of life and ultimately surviving their blood cancer.”

“We continue to encourage the government to support targeted and innovative treatments ensuring Australians diagnosed with a blood cancer have affordable access as quickly as possible,” they said.

Venetoclax has been in development for over 30 years and is based on the Australian discovery that a protein called BCL-2 helps CLL cells survive. Blocking this protein helps to kill and reduce the number of these cancer cells and in turn may slow the spread of CLL.

The Leukaemia Foundation has been funding blood cancer research since 2002 supporting Australian research and researchers with more than $47 million in funding including early work on the precursor to ABT-199 which assisted in the development of Venetoclax.

Last updated on July 15th, 2022

Developed by the Leukaemia Foundation in consultation with people living with a blood cancer, Leukaemia Foundation support staff, haematology nursing staff and/or Australian clinical haematologists. This content is provided for information purposes only and we urge you to always seek advice from a registered health care professional for diagnosis, treatment and answers to your medical questions, including the suitability of a particular therapy, service, product or treatment in your circumstances. The Leukaemia Foundation shall not bear any liability for any person relying on the materials contained on this website.