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Lymphoma

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Lymphoma is a blood cancer that starts in the lymphatic system. It occurs when white blood cells called lymphocytes grow out of control. It can affect your lymph nodes, blood, and organs. There are two categories of lymphoma, Hodgkin lymphoma (HL) and non Hodgkin lymphoma (NHL). There are over 75 subtypes of NHL.

Non Hodgkin lymphoma vs Hodgkin lymphoma

Non Hodgkin lymphoma is more common than Hodgkin lymphoma.

Both are named after the scientist who discovered them.

Non Hodgkin lymphoma is most common in people over the age of 60. Whilst Hodgkin lymphoma is most common in young adults.

The type of cell involved and what it looks like under a microscope defines the type. Hodgkin lymphoma has Reed-Sternberg cells that look like an โ€˜owl eyeโ€™ and usually originate from B lymphocytes. Non Hodgkin lymphoma usually originates from B or T lymphocytes, and natural killer (NK) cells.

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Lymphoma symptoms

Symptoms of lymphoma may include:

  • swollen lymph nodes
  • tiredness for no reason
  • fevers without an infection
  • night sweats
  • itchy skin
  • unexplained weight loss.

Causes of lymphoma

In most cases, we don’t know what causes lymphoma. Some risk factors include:

  • being a certain age
  • being male
  • a family history of lymphoma
  • a weak immune system
  • viruses like human immunodeficiency virus (HIV), and Epstein-Barr virus (EBV).

References

Last updated: 25 May 2026

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How this page exists

The information youโ€™re reading is possible thanks to generous Australians who fundraise, donate, and stand with those facing blood cancer. Their support powers more than research โ€“ it brings life-changing resources and guidance to those who need it most. Developed by the Leukaemia Foundation in consultation with people living with a blood cancer, Leukaemia Foundation support staff, haematology nursing staff and/or Australian clinical haematologists. This content is provided for information purposes only and we urge you to always seek advice from a registered health care professional for diagnosis, treatment and answers to your medical questions, including the suitability of a particular therapy, service, product or treatment in your circumstances. The Leukaemia Foundation shall not bear any liability for any person relying on the materials contained on this website.

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